I didn't really play Holmes much, since I started with AD&D back in '78 with an older brother of a friend who had played OD&D in college and thus didn't need the DMG, but I did have a friend my age who had Holmes and DMed a bit with somewhat hilarious results.
But a lot of people have a fond memory of it, and while there is already one Holmes based retro-clone (Mazes & Perils), there's been another in the works for the last few years, Blueholme Journeymanne, expanding on the rules of Blueholme Compleat (already released and like the original Holmes, only 1-3).
Anyway, it's soon to hit Kickstarter. The game is written, but the KS is to fund original art.
Have no idea how much they are asking for, but they've got the Fiend Folio guy and some other OSR artists, some good, some meh. The link has the full list.